Thrown into desolation, Natalie and her newfound friends form a bond as they struggle to stay alive. With supplies running low, they search the countryside for food and water, but it leads them to a disturbing place. Unknown of the origin of this test site, Natalie realizes she is faced with a more difficult dilemma but must keep her attention on the matters at hand.

As Natalie continues to try and keep peace among the homondie, half-life’s, and the outsiders, a new threat has been revealed. Someone has found Jameson’s serum and is injecting it into the outsiders as they sleep, creating a new breed of human and homondie to use as an army for a takeover. Can Natalie find the culprit that wants to rule it all before their annihilation?